ZFIN Image: Stedman et al., 2009, Fig. 4

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Figure Caption

Fig. 4 Coinjection of irx7 and meis1.1 RNAs leads to ectopic expression of anterior, but not of posterior, hindbrain markers. Embryos uninjected (A, C, E, G, I, K, M, O) or coinjected with meis1.1 and irx7 RNAs (B, D, F, H, J, L, N, P) were processed for ISH with the probes indicated on the left and colour-coded. A–L, O, P show dorsal views of whole embryos with rostral toward the left (C, D, H, I–L, O, P) or toward the top left (A, B, E, F, G). M, N are lateral views of whole embryos with rostral toward the left. Stages are 5 s for A, B, E, F, G, H, K, L, O, P; 15 s for M,N and 100% epiboly for C, D, I, J. Black and red arrowheads point to ectopic gene expression domains (colour-coded). tel: telencephalon.

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Reprinted from Developmental Biology, 327(2), Stedman, A., Lecaudey, V., Havis, E., Anselme, I., Wassef, M., Gilardi-Hebenstreit, P., and Schneider-Maunoury, S., A functional interaction between Irx and Meis patterns the anterior hindbrain and activates krox20 expression in rhombomere 3, 566-577, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.