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Fig. 1 Ethanol treatment causes cyclopia. Embryos were treated at the dome/30% epiboly stage with 2.4% ethanol for 3 h and grown to the 48-h stage. (A) Untreated control embryo. (B) Ethanol-treated embryo with separate, but more closely spaced eyes. (C to E) Ethanol-treated embryos with increasing severity of cyclopia. Embryos are shown in frontal views, dorsal up.
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Reprinted from Developmental Biology, 201, Blader, P. and Strähle, U., Ethanol impairs migration of the prechordal plate in the zebrafish embryo, 185-201, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.