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Fig. 2 fa93e10 expression cycles during ontogenetic fin growth. (A) Whole-mount in situ hybridization illustrating fa93e10 expression in an 8-week-old zebrafish caudal fin. fa93e10 expression (purple staining) is clearly seen at the distal tip of every fin ray (highlighted in six fin rays with black arrows). (B) fa93e10 expression was assessed by whole-mount in situ hybridization in 8- to 35-week-old zebrafish caudal fins (n = 10?150 fins for each age group). (C) In 11 groups of fish from (B) (n = 200), aged 13 weeks (open squares), 16 weeks (solid squares), 24 weeks (solid circles), and 35 weeks (open circles), fa93e10 expression is plotted relative to body size. Each data point represents mean body size (mm) and percent of fins expressing the growth marker fa93e10 for a single group of fish (n = 14?24).
Reprinted from Developmental Biology, 259(2), Goldsmith, M.I., Fisher, S., Waterman, R., and Johnson, S.L., Saltatory control of isometric growth in the zebrafish caudal fin is disrupted in long fin and rapunzel mutants, 303-317, Copyright (2003) with permission from Elsevier. Full text @ Dev. Biol.