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Fig. 3 Cell proliferation is reduced in missense alleles of cx43. Fins were harvested at 3 dpa and stained for H3P detection. A statistically significant reduction in the number of H3P cells was observed for both the Cx43-F30V (p = 0.0001) and the Cx43-P191S (p = 0.0002) alleles in comparison to wild-type. The weaker Cx43-F209I allele was not statistically different from wild-type (p = 0.638). Standard deviation is shown for all alleles.
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Reprinted from Developmental Biology, 317(2), Hoptak-Solga, A.D., Nielsen, S., Jain, I., Thummel, R., Hyde, D.R., and Iovine, M.K., Connexin43 (GJA1) is required in the population of dividing cells during fin regeneration, 541-548, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.