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Fig. S5 Homozygous psm mutant embryos showing high levels of tissue-specific SA-β-gal activity without oxidative stress. Homozygous 3.5 dpf neurodegenerative zebrafish psm mutants (psm2, 5, 6, 8, 9, 10, 11) show much higher levels of punctate SA-β-gal staining throughout their central nervous system compared with wild-type embryos (with PTU). Of note, the muscle atrophy mutant psm7 shows particularly high levels of punctate staining in the trunk region.
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