ZFIN Image: Odenthal et al., 2000, Fig. 1

Image

Figure Caption

Fig. 1 shh in the notochord can induce LFP cells. Lateral views (A, C, E, G) and dorsal views (B, D, F, H) of wild-type (A, B), oep^tz257 (C, D), cyc^tf219 (E, F), and sur^ty68b (G, H) embryos hybridized with probes specific for fkd4 (A–F) and fkd4/shh (G, H) in the pharyngula period (anterior is left). Only ventral neural tube cells overlying the notochord in the trunk of oep and cyc mutants form fkd4-expressing LFP cells (D, F), while in the diencephalon expression is restricted to more dorsal cells (C, E). In sur mutants shh and fkd4 expression in the forebrain appears normal (G), while fkd4 transcription in the trunk is restricted to ventral cells in contact with the notochord (H).

Acknowledgments

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Reprinted from Developmental Biology, 219(2), Odenthal, J., van Eeden, F.J., Haffter, P., Ingham, P.W., and Nüsslein-Volhard, C., Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways, 350-363, Copyright (2000) with permission from Elsevier. Full text @ Dev. Biol.