Fig. 6 Phenotypic rescue of vltm651 embryos by injection of gata1-BAC DNA. (a-c) Lateral views of the ICM regions of embryos stained by in situ hybridization with band3 (x400 magnification). (a) Uninjected phenotypically wild-type embryo (band3-positive), (b) uninjected phenotypically mutant embryo (band3-negative), (c) gata1-BAC injected embryo showing mosaic expression of band3. (d) χ2 analysis of injection data. The null hypothesis tested was that injections did not change the inheritance of the mutant phenotype (i.e., recessive or 1:3 mutant to wild-type ratio). The data shown indicate the number of embryos obtained for each phenotype, and the numbers shown in parentheses are the number of embryos expected for each phenotype assuming recessive inheritance.
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