ZFIN Image: Starr et al., 2004, Fig. 2

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Figure Caption

Fig. 2 Disruption of lateral-line hair cells by the ru848 mutation. (A) Transmitted-light illumination shows the grossly normal structure of the otocysts in WT (Upper) and mutant (Lower) larvae at 5 dpf. (B) Under fluorescent illumination, the neuromasts form a characteristic pattern on the head of a WT larva (Upper) labeled with 4-Di-2-ASP. The mutant larva (Lower) bears only two brightly labeled neuromasts (arrowheads). (C) In a scanning electron micrograph, the center of a WT neuromast at 6 dpf displays hair bundles with short stereocilia and long kinocilia. The neuromast is enclosed by two periderm cells. (D) In a mutant, the periderm cells appear relatively normal, but in the center of the neuromast stand only two kinocilia that are much shorter than those seen in the WT. (Scale bars: 200 μm, A and B; 10 μm, C and D.)

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA