ZFIN Image: Hjorth et al., 2001, Fig. 6

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Figure Caption

Fig. 6 The early axon scaffold exhibits a dynamic spatial relationship with gene expression domains. Confocal laser scanning microscope Z-series images of lateral views of 24-hpf whole-mount zebrafish brains double labelled for the expression of the HNK-1 epitope (green) and (A) shh, (B) nkx2.2, (C) dlx2, (D) pax6, (E) otx2, (F) otx3, (G) hlx1, and (H) axial in red. Rostral is to the right and dorsal is to the top. AC, anterior commissure; DVDT, dorsoventral diencephalic tract; MLF, medial longitudinal fasciculus; POC, postoptic commissure; SOT, supraoptic tract; TPC, tract of the posterior commissure; TPOC, tract of the postoptic commissure; VC, ventral commissure, vcc, ventrocaudal cluster. Bar: 50 μm in A–C, E, F, G; 20 μm in D, H.

Acknowledgments

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Reprinted from Developmental Biology, 229(2), Hjorth, J.T. and Key, B., Are pioneer axons guided by regulatory gene expression domains in the zebrafish forebrain? High-resolution analysis of the patterning of the zebrafish brain during axon tract formation, 271-286, Copyright (2001) with permission from Elsevier. Full text @ Dev. Biol.