Fig. 1

Fig. 1 Establishment of CB1 expression in the peripheral nervous system. (A) Side view of a stage 19 whole embryos showing expression of CB1 in only the trigeminal and vestibuloaccoustic ganglia. (B) Higher power view of the head and (C) of the trunk. (D) Side view of a stage 20 embryo indicating that expression was additionally found in the geniculate, petrosal and nodose at this stage and had initiated in the dorsal root ganglia. (E) Higher power view of a stage 20 head showing expression in the cranial ganglia. (F) Higher power view of the trunk at stage 20 showing expression in the DRGs. (G) Side view of a stage 21 embryo, showing expression in the cranial sensory ganglia, the DRGs and the forming sympathetic ganglia. (H) Higher power view showing expression in the cranial ganglia. (I) Higher power view of the trunk highlighting the more pronounced expression in the DRGs and sympathetic ganglia had become apparent in the sympathetic ganglia. White asterisks highlight the positions of the DRGs, the black asterisk the position of the sympathetic chain. Abbreviations: T—trigeminal, VA—vestibuloaccoustic, G—geniculate, P—petrosal, N—nodose, DRGs—dorsal root ganglia.