Fig. 7

Fig. 7 Loss of nok nuclear import and export signals does not affect epithelial maintenance. Phenotypes of (A) wt, (B) nok^s305 mutant, (C) nok^s305 mutant rescued with nok^ΔNLS mRNA or with (D) nok^{ΔPatj NLS} mRNA at 36 hpf. The straight body form is rescued in nok^ΔNLS mutants (C) but not in nok^{ΔPatj NLS} mutants (D). Insets depict details of RPE from each corresponding embryo. The cobble-stone like appearance of RPE tissue surrounding the neural retina is severely disrupted and displays wholes in (B) nok^s305 but this phenotype is partially complemented in (C) nok^ΔNLS or (D) nok^{ΔPatj NLS} mutants. E: Summary of rescue efficiencies of the different deletion mutants. Mutant phenotypes for nok^ΔNES are similar to nok^{ΔPatj NLS} (not shown).