ZFIN Image: Iovine et al., 2005, Fig. 4

Image

Figure Caption

Fig. 4 cx43-MO injections cause defects in heart morphology and hematopoiesis. Representative photographs of each morpholino injection trial are shown. (A–C) Wild-type embryos injected with 1.5 ng of standard control morpholino. (D–F) Wild-type embryos injected with 1.5 ng of cx43-MO. (G–I) Wild-type embryos injected with 0.25 ng of cx43-MO. (J–L) sof^b123 embryos injected with 0.25 ng cx43-MO. The left column (heart) shows the heart morphology phenotype at 72 hpf. The atrium is outlined in purple, and the ventricle is outlined in green. The middle column (heart) shows higher magnification views of the hearts in the left column. The right column (blood) shows o-dianisidine staining of globin (representing red blood cells) in injected embryos at 72 hpf.

Acknowledgments

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Reprinted from Developmental Biology, 278(1), Iovine, M.K., Higgins, E.P., Hindes, A., Coblitz, B., and Johnson, S.L., Mutations in connexin43 (GJA1) perturb bone growth in zebrafish fins, 208-219, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.