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Fig. 3

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ZDB-IMAGE-071001-42
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Figures for Semina et al., 2006
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Fig. 3  Laminin alpha 1 expression during eye development. In situ hybridization for lama1 transcripts (purple) was investigated at (A) 24 hpf, (B) 48 hpf, and (C) 72 hpf. Laminin-1 immunoreactivity (red) was examined at (D) 24 hpf, (E) 48 hpf, and (F) 72 hpf and found to be associated with the cornea, sclera, lens capsule, outer segments of photoreceptors, and optic nerve (arrows in panel E). By 72 hpf, immunoreactivity was also observed in the developing anterior segment angle (arrowheads in panel F).

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Reprinted from Developmental Biology, 299(1), Semina, E.V., Bosenko, D.V., Zinkevich, N.C., Soules, K.A., Hyde, D.R., Vihtelic, T.S., Willer, G.B., Gregg, R.G., and Link, B.A., Mutations in laminin alpha 1 result in complex, lens-independent ocular phenotypes in zebrafish, 63-77, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.