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Figure Caption
Fig. 7 PGC migration is aberrant when Stau2 function is disrupted. Time-lapse microscopy on GST-injected embryos (A–D) shows clusters of GFP:nos expressing cells (large white arrowheads) that migrate to the gonadal ridge. In contrast, in embryos injected with Stau2 RBD5 (E–H), GFP expressing cells fail to form clusters, remain dispersed (small white arrowheads in panels E, F, G), do not migrate to the gonadal ridge, and eventually disappear (H). Dorsal views of 1 somite stage (A, E), 5 somite stage (B, F), 10 somite stage (C, G), and 20 somite stage (D, H) embryos. Scale bars, 100 μm.
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Reprinted from Developmental Biology, 292(2), Ramasamy, S., Wang, H., Quach, H.N., and Sampath, K., Zebrafish Staufen1 and Staufen2 are required for the survival and migration of primordial germ cells, 393-406, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.