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Figure Caption
Fig. 6 Induction of myoD by RA requires translation of a protein intermediate. 10-somite stage embryos, oriented as in Fig. 2. (A–B) RA activates expression of myoD in somites and psm (bracket) (B) compared to wild-type (A). (C–D) Cycloheximide (CHX) decreases expression of myoD in somites (C) and severely reduces myoD induction by RA in anterior psm (D). Scale bar: in panel A, 100 μm for panels A–D.
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Reprinted from Developmental Biology, 289(1), Hamade, A., Deries, M., Begemann, G., Bally-Cuif, L., Genet, C., Sabatier, F., Bonnieu, A., and Cousin, X., Retinoic acid activates myogenesis in vivo through Fgf8 signalling, 127-140, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.