ZFIN Image: Ramel et al., 2005, Fig. 1

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Figure Caption

Fig. 1 Wnt8 and BMP2b are required to maintain axial/non-axial polarity. Morphology of bud stage embryos. Genotypes are indicated above each column. A–D: dorsal views. F–I: lateral views, dorsal right. Arrows in panels A–C indicate the width of the notochord when visible. Double arrows in panels F–I indicate the length of the A/P axis, asterisks indicate rostral edge of anterior axial mesoderm. Note the shortened axis of wnt8 MO embryos (C, H) and the posterior displacement of the axis in wnt8 MO; swr/+ embryos (D, I). wnt8 MO; swr/swr embryos display a large mass of cells at the animal pole (arrows in E and J) and do not have a recognizable D/V polarity.

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Acknowledgments

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Reprinted from Developmental Biology, 287(2), Ramel, M.C., Buckles, G.R., Baker, K.D., and Lekven, A.C., WNT8 and BMP2B co-regulate non-axial mesoderm patterning during zebrafish gastrulation, 237-248, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.