ZFIN Image: Wang et al., 2006, Fig. 1

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Figure Caption

Fig. 1 MEF2A morphants display a downward tail curvature and have U-shaped posterior somites although the somite borders are generated normally. (A–F) Lateral views with anterior to the left. The overall morphology of a MEF2A MO-injected (A and C) and control MO-injected (B and D) embryos at 32 hpf (A and B) and 96 hpf (C and D). Note that the MEF2A morphants display a downward tail curvature (A and C) (n = 50 embryos). (E and F) Lateral views of titin expression, which marks each segment border in MEF2A GT-MO-injected (E) and control MO-injected (F) embryos at 96 hpf. Injection of control MO results in chevron-shaped somites with an angle of 95° (n = 20 embryos), while injection of MEF2A GT-MO results in a more obtuse angle of the somite (130°) (n = 19 embryos).

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Acknowledgments

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Reprinted from Mechanisms of Development, 123(10), Wang, Y., Qian, L., Dong, Y., Jiang, Q., Gui, Y., Zhong, T.P., and Song, H., Myocyte-specific enhancer factor 2A is essential for zebrafish posterior somite development, 783-791, Copyright (2006) with permission from Elsevier. Full text @ Mech. Dev.