ZFIN Image: Cunliffe et al., 2006, Fig. 5

Image

Figure Caption

Fig. 5 Expression of pax6a is up-regulated in the hindbrain of hdac1 mutant embryos. (A–H) Expression of pax6a in hindbrain of (A,C,E,G) wild-type sibling, (B,D,F,H) hdac1 mutant embryos at (A,B) 27 hpf, (C,D,G,H) 35 hpf and (E,F) 51 hpf. Panels A–F show transverse sections through the hindbrain of embryos at the level of rhombomere 5; panels G,H show dorsal views of (G) wild-type and (H) hdac1 mutant hindbrain, demonstrating that expression of pax6a is up-regulated throughout the length of the hindbrain as a consequence of the hdac1 mutation. Particularly strong ectopic expression of pax6a can be seen in dorso-medial and ventro-lateral (arrows in B) territories of rhombomere 5 in the hdac1 mutant hindbrain.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Mechanisms of Development, 123(1), Cunliffe, V.T., and Casaccia-Bonnefil, P., Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS, 24-30, Copyright (2006) with permission from Elsevier. Full text @ Mech. Dev.