ZFIN Image: Feng et al., 2006, Fig. 4

Image

Figure Caption

Fig. 4 Wild-type slow muscle fibers do not rescue the number of Pax7+ myogenic precursors in smu(smo)-/-. A smu(smo)-/- host embryo with transplanted wild-type donor cells (blue) was labeled with antibodies for Prox1 (red) and Pax7 (green). (A) A lateral view of 6 mid-trunk somites, some of which contain donor-derived (blue), Prox1-positive (red) embryonic slow muscle fibers. (B) The same embryo labeled for Pax7, to show myogenic precursor nuclei (green), arrowheads point to neural crest cells. (C) The merged image of panels A and B, the numbers on the bottom indicate the number of Pax7+ myogenic precursor nuclei within the corresponding somite, compare to Fig. 2G. Anterior to the left, dorsal up; scale bar = 50 μm.

Acknowledgments

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Reprinted from Developmental Biology, 300(2), Feng, X., Adiarte, E.G., and Devoto, S.H., Hedgehog acts directly on the zebrafish dermomyotome to promote myogenic differentiation, 736-746, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.