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Fig. 1 Dvl1-/-; Dvl2-/- mutants displayed reduced length-to-width ratio during neurulation. (A-D) Five- to eight-somite stage Dvl1-/-; Dvl2+/- or Dvl1-/-; Dvl2+/+ control embryos. (A'-D') Dvl1-/-; Dvl2-/- mutants of equivalent somite stages. Floor plates are expanded in Dvl1-/-; Dvl2-/- mutants. (E) Length-to-width ratio (LWR) changes of control and Dvl1-/-; Dvl2-/- mutant embryos at different somite stage during neurulation. Each point represents the average of at least three separate embryos. The error bars represent standard deviation. *P<0.05; **P<0.01.
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