GENOTYPE
vcc2Tg
- ID
- ZDB-GENO-131010-4
- Name
- vcc2Tg
- Previous Name
- Background
- Unspecified
- Affected Genomic Region
- Current Source
- No data available
Notes
Genotype Composition
| Genomic Feature | Construct | Lab of Origin | Zygosity | Parental Zygosity |
|---|---|---|---|---|
| vcc2Tg | Tg(myl7:Hsa.SCN5A_D1275N-MYC,cryaa:EGFP) | Fatkin Lab | unknown | Unknown |
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Fish utilizing vcc2Tg
| Fish | Affected Genomic Region | Phenotype | Gene Expression |
|---|---|---|---|
| vcc2Tg | 4 figures from 3 publications | ||
| vcc2Tg + MO1-scn12aa + MO1-scn5lab | Fig. 4 from Huttner et al., 2013 |
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- Le, T., Zhang, J., Nguyen, A.H., Trigo Torres, R.S., Vo, K., Dutt, N., Lee, J., Ding, Y., Xu, X., Lau, M.P.H., Cao, H. (2021) A novel wireless ECG system for prolonged monitoring of multiple zebrafish for heart disease and drug screening studies. Biosensors & bioelectronics. 197:113808
- Yan, J., Li, H., Bu, H., Jiao, K., Zhang, A.X., Le, T., Cao, H., Li, Y., Ding, Y., Xu, X. (2020) Aging-associated sinus arrest and sick sinus syndrome in adult zebrafish. PLoS One. 15:e0232457
- Huttner, I.G., Trivedi, G., Jacoby, A., Mann, S.A., Vandenberg, J.I., and Fatkin, D. (2013) A transgenic zebrafish model of a human cardiac sodium channel mutation exhibits bradycardia, conduction-system abnormalities and early death. Journal of Molecular and Cellular Cardiology. 61:123-32
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