Gene

acvr2aa

ID
ZDB-GENE-980526-227
Name
activin A receptor type 2Aa
Symbol
acvr2aa Nomenclature History
Previous Names
  • actr2a (1)
  • acvr2
  • acvr2a
  • etID22865.9 (1)
  • wu:fa02e10
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have activin binding activity and activin-activated receptor activity. Involved in cartilage development; hindbrain development; and neural crest cell migration. Predicted to localize to activin receptor complex. Is expressed in several structures, including blastoderm; blastomere; gut; oral region; and ovarian follicle. Human ortholog(s) of this gene implicated in colon cancer. Orthologous to human ACVR2A (activin A receptor type 2A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Albertson et al., 2005
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acvr2aa Human Ortholog
No data available
Associated With acvr2aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000472 Activin types I and II receptor domain
Domain IPR000719 Protein kinase domain
Family IPR000333 Ser/Thr protein kinase, TGFB receptor
Family IPR017194 Transforming growth factor-beta receptor, type II
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Activin types I and II receptor domain Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Ser/Thr protein kinase, TGFB receptor Transforming growth factor-beta receptor, type II
UniProtKB:F1R4D0 538
UniProtKB:F1QG01 514
UniProtKB:A9CAY0 514
UniProtKB:Q56E96 495
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations