Gene
plcb1
- ID
- ZDB-GENE-231129-3
- Name
- phospholipase C beta 1
- Symbol
- plcb1 Nomenclature History
- Previous Names
-
- si:ch1073-140o9.2
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity and phosphatidylinositol phospholipase C activity. Predicted to act upstream of or within intracellular signal transduction and lipid catabolic process.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Scheldeman et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain |
| Domain | IPR014815 | Phospholipase C-beta, C-terminal domain |
| Domain | IPR015359 | Phosphoinositide-specific phospholipase C, EF-hand-like domain |
| Domain | IPR037862 | PLC-beta, PH domain |
| Domain | IPR053945 | Phosphoinositide phospholipase C beta 1-4-like, EF-hand domain |
| Family | IPR001192 | Phosphoinositide phospholipase C family |
| Family | IPR016280 | Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR042531 | Phospholipase C-beta, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2 domain | C2 domain superfamily | EF-hand domain pair | Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta | Phosphatidylinositol-specific phospholipase C, X domain | Phosphoinositide phospholipase C beta 1-4-like, EF-hand domain | Phosphoinositide phospholipase C family | Phosphoinositide-specific phospholipase C, EF-hand-like domain | Phospholipase C-beta, C-terminal domain | Phospholipase C-beta, C-terminal domain superfamily | PLC-beta, PH domain | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32T5Q2 | InterPro | 1089 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plcb1-202
(1)
|
Ensembl | 3,021 nt | ||
| mRNA |
si:ch1073-140o9.2-201
(1)
|
Ensembl | 99 nt |
Interactions and Pathways
No data available
Plasmids
No data available