ZFIN is now using GRCz12tu for Genomic Data
Gene
lplb
- ID
- ZDB-GENE-230322-2
- Name
- lipoprotein lipase b
- Symbol
- lplb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable apolipoprotein binding activity; glycerophospholipid phospholipase A1 activity; and lipoprotein lipase activity. Predicted to be involved in several processes, including cholesterol homeostasis; plasma lipoprotein particle remodeling; and triglyceride catabolic process. Predicted to be located in plasma membrane. Predicted to be active in extracellular region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial combined hyperlipidemia | Alliance | Combined hyperlipidemia, familial | 144250 |
| familial lipoprotein lipase deficiency | Alliance | Lipoprotein lipase deficiency | 238600 |
| familial lipoprotein lipase deficiency | Alliance | [High density lipoprotein cholesterol level QTL 11] | 238600 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001024 | PLAT/LH2 domain |
| Domain | IPR013818 | Lipase |
| Domain | IPR033906 | Lipase, N-terminal |
| Family | IPR000734 | Triacylglycerol lipase family |
| Family | IPR002330 | Lipoprotein lipase |
| Family | IPR016272 | Lipase, LIPH-type |
| Homologous_superfamily | IPR029058 | Alpha/Beta hydrolase fold |
| Homologous_superfamily | IPR036392 | PLAT/LH2 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | Lipase | Lipase, LIPH-type | Lipase, N-terminal | Lipoprotein lipase | PLAT/LH2 domain | PLAT/LH2 domain superfamily | Triacylglycerol lipase family |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0G2KRU2 | InterPro | 530 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance