Gene
ythdc2
- ID
- ZDB-GENE-220119-1
- Name
- YTH domain containing 2
- Symbol
- ythdc2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity and helicase activity. Acts upstream of or within spermatogenesis. Orthologous to human YTHDC2 (YTH N6-methyladenosine RNA binding protein C2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Li et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001374 | R3H domain |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR007275 | YTH domain |
| Domain | IPR007502 | Helicase-associated domain |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR011709 | DEAD-box helicase, OB fold |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR034083 | DExH-box ATP-dependent RNA helicase, R3H domain |
| Domain | IPR048333 | Helicase associated domain (HA2), winged-helix domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Homologous_superfamily | IPR036867 | R3H domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat-containing domain superfamily | DEAD-box helicase, OB fold | DEAD/DEAH box helicase domain | DExH-box ATP-dependent RNA helicase, R3H domain | Helicase-associated domain | Helicase associated domain (HA2), winged-helix domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | R3H domain | R3H domain superfamily | YTH domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q954 | InterPro | 1381 | ||||||||||||
| UniProtKB:A0A8M9PKP9 | InterPro | 1130 | ||||||||||||
| UniProtKB:A0A8M9PY86 | InterPro | 1055 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ythdc2-201
(1)
|
Ensembl | 4,245 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance