pde2a

ID

ZDB-GENE-190819-1

Name

phosphodiesterase 2A

Symbol

pde2a Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity and protein homodimerization activity. Predicted to be involved in several processes, including cGMP catabolic process; negative regulation of signal transduction; and regulation of mitochondrion organization. Predicted to act upstream of or within signal transduction. Predicted to be active in several cellular components, including mitochondrion; perinuclear region of cytoplasm; and synaptic membrane.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pde2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Intellectual developmental disorder with paroxysmal dyskinesia or seizures	619150

Associated With pde2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PCP4	InterPro	870
UniProtKB:A0AC58HE18	InterPro	924
UniProtKB:A0AC58HE19	InterPro	933
UniProtKB:A0AC58HE26	InterPro	916
UniProtKB:A0AC58HE28	InterPro	944
UniProtKB:A0AC58HE30	InterPro	916
UniProtKB:A0AC58HE52	InterPro	916