ZFIN is now using GRCz12tu for Genomic Data
Gene
acvr1c
- ID
- ZDB-GENE-181207-1
- Name
- activin A receptor type 1C
- Symbol
- acvr1c Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable activin receptor activity, type I. Predicted to be involved in activin receptor signaling pathway; cellular response to growth factor stimulus; and nervous system development. Predicted to act upstream of or within cell surface receptor protein serine/threonine kinase signaling pathway and protein phosphorylation. Predicted to be located in membrane. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane. Is expressed in heart.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000472 | Activin types I and II receptor domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR003605 | GS domain |
| Family | IPR000333 | Ser/Thr protein kinase, TGFB receptor |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR045860 | Snake toxin-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Activin types I and II receptor domain | GS domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Ser/Thr protein kinase, TGFB receptor | Snake toxin-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PSI8 | InterPro | 491 | ||||||||
| UniProtKB:A0AC58GFM5 | InterPro | 444 | ||||||||
| UniProtKB:A0AC58GFM6 | InterPro | 444 | ||||||||
| UniProtKB:A0AC58GFN7 | InterPro | 363 | ||||||||
| UniProtKB:A0AC58GFN8 | InterPro | 444 | ||||||||
| UniProtKB:A0AC58GFN9 | InterPro | 410 | ||||||||
| UniProtKB:A0AC58GFP0 | InterPro | 363 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
acvr1c-201
(1)
|
Ensembl | 2,522 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers