Gene
ch25hl3
- ID
- ZDB-GENE-180119-1
- Name
- cholesterol 25-hydroxylase like 3
- Symbol
- ch25hl3 Nomenclature History
- Previous Names
-
- ch25ha (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable iron ion binding activity and oxidoreductase activity. Predicted to act upstream of or within lipid biosynthetic process. Predicted to be located in membrane. Is expressed in gill; intestine; kidney; liver; and spleen.
- Genome Resources
-
- Alliance (1)
- Gene:100005337 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Pereiro et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Fatty acid hydroxylase | Sterol Desaturase and Related Enzymes |
|---|---|---|---|---|
| UniProtKB:F1QE73 | InterPro | 267 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-204L11 | Pereiro et al., 2017 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001344388 (1) | 1095 nt | ||
| Genomic | GenBank:CR762390 (1) | 167774 nt | ||
| Polypeptide | UniProtKB:F1QE73 (1) | 267 aa |
- Comparative Orthology
- Alliance
- Keatinge, M., Tsarouchas, T.M., Munir, T., Porter, N.J., Larraz, J., Gianni, D., Tsai, H.H., Becker, C.G., Lyons, D.A., Becker, T. (2021) CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury. PLoS Genetics. 17:e1009515
- Wu, X., Xiong, F., Fang, H., Zhang, J., Chang, M. (2021) Crosstalks between NOD1 and Histone H2A Contribute to Host Defense against Streptococcus agalactiae Infection in Zebrafish. Antibiotics (Basel, Switzerland). 10(7):
- Pereiro, P., Forn-Cuní, G., Dios, S., Coll, J., Figueras, A., Novoa, B. (2017) Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish. Antiviral Research. 145:146-159
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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