ZFIN is now using GRCz12tu for Genomic Data
Gene
nlrp3l.1
- ID
- ZDB-GENE-180104-12
- Name
- NACHT, LRR and PYD domains-containing protein 3-like, tandem duplicate 1
- Symbol
- nlrp3l.1 Nomenclature History
- Previous Names
-
- nlrp3l
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to act upstream of or within inflammatory response; innate immune response; and regulation of apoptotic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Frame et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Frame et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001315 | CARD domain |
| Domain | IPR007111 | NACHT nucleoside triphosphatase |
| Domain | IPR029495 | NACHT-associated domain |
| Domain | IPR033516 | CARD8/ASC/NALP1, CARD domain |
| Domain | IPR041267 | NACHT, LRR and PYD domains-containing protein, helical domain HD2 |
| Family | IPR050637 | NLRP family, innate immunity and inflammation regulators |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | CARD8/ASC/NALP1, CARD domain | CARD domain | Death-like domain superfamily | Leucine-rich repeat domain superfamily | NACHT-associated domain | NACHT, LRR and PYD domains-containing protein, helical domain HD2 | NACHT nucleoside triphosphatase | NLRP family, innate immunity and inflammation regulators | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BIU4 | InterPro | 836 | |||||||||
| UniProtKB:A0A8M3B7W6 | InterPro | 977 | |||||||||
| UniProtKB:A0AB32T452 | InterPro | 954 | |||||||||
| UniProtKB:A0AB32T6I5 | InterPro | 993 | |||||||||
| UniProtKB:A0AB32T7T1 | InterPro | 1021 | |||||||||
| UniProtKB:A0AB32TB25 | InterPro | 998 | |||||||||
| UniProtKB:A0AB32TB65 | InterPro | 958 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nlrp3l.1-201
(1)
|
Ensembl | 2,875 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers