gabra2b

ID

ZDB-GENE-171102-1

Name

gamma-aminobutyric acid type A receptor subunit alpha2b

Symbol

gabra2b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Is expressed in brain; cerebellum; diencephalon; optic tectum; and telencephalon.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gabra2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
alcohol dependence	Alliance	{Alcohol dependence, susceptibility to}	103780
developmental and epileptic encephalopathy 78	Alliance	Developmental and epileptic encephalopathy 78	618557

Associated With gabra2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018000	Neurotransmitter-gated ion-channel, conserved site
Domain	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
Domain	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
Domain	IPR047024	Gamma-aminobutyric acid receptor subunit alpha 1-6, transmembrane domain
Family	IPR001390	Gamma-aminobutyric-acid A receptor, alpha subunit
Family	IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Family	IPR006201	Neurotransmitter-gated ion-channel
Homologous_superfamily	IPR036719	Neurotransmitter-gated ion-channel transmembrane domain superfamily
Homologous_superfamily	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Homologous_superfamily	IPR038050	Neuronal acetylcholine receptor