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ZIRC
ZFIN ID: ZDB-GENE-170530-1
Gene Name: endoglin
Gene Symbol: eng
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Unmapped
Note: Gene introduced in Sugden et al, Nat Cell Biol. 2017.
AUTOMATED DESCRIPTION
Involved in blood vessel morphogenesis; cellular response to mechanical stimulus; and endothelial cell morphogenesis. Predicted to localize to the integral component of membrane and plasma membrane.
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
mu130 Small Deletion Unknown Unknown TALEN
mu131 Small Deletion Unknown Unknown TALEN
mu132 Indel Unknown Unknown TALEN
Targeting reagents:
DISEASE ASSOCIATED WITH eng HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
hereditary hemorrhagic telangiectasia Telangiectasia, hereditary hemorrhagic, type 1 187300
DISEASE ASSOCIATED WITH eng VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process blood vessel morphogenesis (more)
Cellular Component integral component of membrane (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001507 (1)
  • Pfam:PF00100 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM eng
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021476706 (1)
    Genomic GenBank:CU927890 (1) 98187bp
    Select Tool
    Polypeptide UniProtKB:A0A1Z2R986 (1) 559aa
    Sequence Information (all 31)
    OTHER eng GENE PAGES
  • Alliance (1)
  • Gene:101883074 (1)
  • ORTHOLOGY for eng ( Unmapped )
    CITATIONS (7)