Gene

trhde.1

ID
ZDB-GENE-170406-2
Name
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
Symbol
trhde.1 Nomenclature History
Previous Names
  • trhde1-1 (1)
  • si:ch211-149p5.1
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be active in cytoplasm; extracellular space; and membrane. Orthologous to human TRHDE (thyrotropin releasing hormone degrading enzyme).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa40298Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa45176Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With trhde.1 Human Ortholog
No data available
Associated With trhde.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR014782 Peptidase M1, membrane alanine aminopeptidase
Domain IPR024571 ERAP1-like C-terminal domain
Domain IPR045357 Aminopeptidase N-like , N-terminal domain
Family IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
Family IPR034016 Aminopeptidase N-type
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Domain Details Per Protein
Protein Additional Resources Length Aminopeptidase N-like , N-terminal domain Aminopeptidase N-like , N-terminal domain superfamliy Aminopeptidase N-type ERAP1-like C-terminal domain Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase Peptidase M1 family aminopeptidases Peptidase M1, membrane alanine aminopeptidase Peptidase M4/M1, CTD superfamily
UniProtKB:A0A8M1Q7Z4 InterPro 994
UniProtKB:A0A8M9PET6 InterPro 415
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 4
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA trhde.1-201 (1)
Ensembl
Ensembl 2,841 nt
ZFIN BLAST
mRNA trhde.1-202 (1)
Ensembl
Ensembl 2,952 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-149P5ZFIN Curated Data
Contained inBACDKEYP-79F4ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_001345421 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicRefSeq:NW_018395231 (1)
MegaBLAST
PolypeptideUniProtKB:A0A8M1Q7Z4 (1)994 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
No data available
Citations
TSV
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