Gene
sprtn
- ID
- ZDB-GENE-170317-1
- Name
- SprT-like N-terminal domain
- Symbol
- sprtn Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity; metalloendopeptidase activity; and polyubiquitin modification-dependent protein binding activity. Acts upstream of or within DNA damage response. Predicted to be located in chromatin. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Ruijs-Aalfs syndrome. Orthologous to human SPRTN (SprT-like N-terminal domain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ruijs-Aalfs syndrome | Alliance | Ruijs-Aalfs syndrome | 616200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Rad18, zinc finger UBZ4-type | Spartan-like, zinc binding domain | SprT-like | SprT-like domain-containing protein Spartan |
|---|---|---|---|---|---|
|
UniProtKB:A0A0G2L7I0
|
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available