ZFIN is now using GRCz12tu for Genomic Data
Gene
rnf31
- ID
- ZDB-GENE-170316-1
- Name
- ring finger protein 31
- Symbol
- rnf31 Nomenclature History
- Previous Names
-
- hoip (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable linear polyubiquitin binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin protein ligase activity. Acts upstream of or within cilium assembly. Predicted to be part of LUBAC complex. Human ortholog(s) of this gene implicated in immunodeficiency 115. Orthologous to human RNF31 (ring finger protein 31).
- Genome Resources
-
- Alliance (1)
- Gene:100334178 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Shen et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 115 | Alliance | Immunodeficiency 115 with autoinflammation | 620632 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M3B0A7 | InterPro | 1052 |
| UniProtKB:A0AC58HKE9 | InterPro | 1052 |
| UniProtKB:A0AC58HKG8 | InterPro | 1052 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance