Gene
iqsec2a
- ID
- ZDB-GENE-170302-3
- Name
- IQ motif and Sec7 domain ArfGEF 2a
- Symbol
- iqsec2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to be involved in regulation of ARF protein signal transduction. Predicted to localize to cytoplasm.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 1 | Alliance | Mental retardation, X-linked 1/78 | 309530 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Domain | IPR000904 | Sec7 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR033742 | IQ motif and SEC7 domain-containing protein, PH domain |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR023394 | Sec7, C-terminal domain superfamily |
| Homologous_superfamily | IPR035999 | Sec7 domain superfamily |
Domain Details Per Protein
| Protein | Length | IQ motif and SEC7 domain-containing protein, PH domain | IQ motif, EF-hand binding site | PH-like domain superfamily | Pleckstrin homology domain | Sec7, C-terminal domain superfamily | Sec7 domain | Sec7 domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0G2L9N5
|
||||||||
|
UniProtKB:A0A2R8QNV2
|
825 | |||||||
|
UniProtKB:A0A2R8QUT2
|
1281 | |||||||
|
UniProtKB:A0A2R8QGT6
|
1013 | |||||||
|
UniProtKB:A0A2R8Q8B1
|
1487 | |||||||
|
UniProtKB:A0A2R8Q462
|
858 | |||||||
|
UniProtKB:A0A2R8Q8W8
|
1492 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available