Gene
iqsec2a
- ID
- ZDB-GENE-170302-3
- Name
- IQ motif and Sec7 domain ArfGEF 2a
- Symbol
- iqsec2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within regulation of ARF protein signal transduction. Predicted to be located in cytoplasm.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 1 | Alliance | Intellectual developmental disorder, X-linked 1 | 309530 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000904 | Sec7 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR033742 | IQ motif and SEC7 domain-containing protein, PH domain |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR023394 | Sec7, C-terminal domain superfamily |
| Homologous_superfamily | IPR035999 | Sec7 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | IQ motif and SEC7 domain-containing protein, PH domain | PH-like domain superfamily | Pleckstrin homology domain | Sec7, C-terminal domain superfamily | Sec7 domain | Sec7 domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0G2L9N5 | InterPro | |||||||
| UniProtKB:A0A8M3AV51 | InterPro | 1639 | ||||||
| UniProtKB:A0A8M6YZZ1 | InterPro | 1140 | ||||||
| UniProtKB:A0A8M6Z2A5 | InterPro | 1491 | ||||||
| UniProtKB:A0A8M6Z7T7 | InterPro | 1629 | ||||||
| UniProtKB:A0A8M6Z874 | InterPro | 1487 | ||||||
| UniProtKB:A0A8M9PS64 | InterPro | 1130 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
iqsec2-201
(1)
|
Ensembl | 3,846 nt | ||
| mRNA |
iqsec2-202
(1)
|
Ensembl | 4,890 nt | ||
| mRNA |
iqsec2-203
(1)
|
Ensembl | 5,084 nt | ||
| mRNA |
iqsec2-204
(1)
|
Ensembl | 4,665 nt | ||
| mRNA |
iqsec2-205
(1)
|
Ensembl | 3,042 nt | ||
| mRNA |
iqsec2-206
(1)
|
Ensembl | 2,577 nt | ||
| mRNA |
iqsec2-207
(1)
|
Ensembl | 2,478 nt |
Interactions and Pathways
No data available
Plasmids
No data available