Gene

dtx4a

ID

ZDB-GENE-160728-59

Name

deltex 4, E3 ubiquitin ligase a

Symbol

dtx4a Nomenclature History

Previous Names

dtx1 (1)
si:ch211-119e14.2 (2)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within Notch signaling pathway. Predicted to be located in cytoplasm. Orthologous to human DTX4 (deltex E3 ubiquitin ligase 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dtx4a Human Ortholog

No data available

Associated With dtx4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR004170	WWE domain
Domain	IPR018123	WWE domain, subgroup
Domain	IPR018957	Zinc finger, C3HC4 RING-type
Domain	IPR039396	Deltex, C-terminal
Family	IPR039398	Deltex family
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR037197	WWE domain superfamily
Homologous_superfamily	IPR039399	Deltex, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Deltex, C-terminal	Deltex, C-terminal domain superfamily	Deltex family	WWE domain	WWE domain, subgroup	WWE domain superfamily	Zinc finger, C3HC4 RING-type	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type
UniProtKB:B2KJ26 InterPro	704

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dtx4a-203 (1) Ensembl	Ensembl	4,955 nt	Select Tool ZFIN BLAST
mRNA	si:ch211-119e14.2-001 (1) Ensembl	Ensembl	4,957 nt	Select Tool ZFIN BLAST
ncRNA	si:ch211-119e14.2-002 (1) Ensembl	Ensembl	921 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations