Gene
timp4.2
- ID
- ZDB-GENE-160114-61
- Name
- TIMP metallopeptidase inhibitor 4, tandem duplicate 2
- Symbol
- timp4.2 Nomenclature History
- Previous Names
-
- si:ch73-206h6.3
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity and metalloendopeptidase inhibitor activity. Predicted to act upstream of or within negative regulation of peptidase activity. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human TIMP4 (TIMP metallopeptidase inhibitor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR030490 | Tissue inhibitor of metalloproteinase, conserved site |
| Domain | IPR001134 | Netrin domain |
| Family | IPR001820 | Protease inhibitor I35 (TIMP) |
| Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
| Homologous_superfamily | IPR027465 | Proteinase inhibitor I35b (TIMP), C-terminal |
Domain Details Per Protein
| Protein | Additional Resources | Length | Netrin domain | Protease inhibitor I35 (TIMP) | Proteinase inhibitor I35b (TIMP), C-terminal | Tissue inhibitor of metalloproteinase, conserved site | Tissue inhibitor of metalloproteinases-like, OB-fold |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1P9Q2 | InterPro | 187 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
timp4.2-201
(1)
|
Ensembl | 940 nt |
Interactions and Pathways
No data available
Plasmids
No data available