ZFIN is now using GRCz12tu for Genomic Data
Gene
wnk2
- ID
- ZDB-GENE-160114-3
- Name
- WNK lysine deficient protein kinase 2
- Symbol
- wnk2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable potassium channel inhibitor activity and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; monoatomic ion homeostasis; and regulation of metal ion transport. Predicted to be active in cytoplasm. Orthologous to human WNK2 (WNK lysine deficient protein kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR024678 | Serine/threonine-protein kinase OSR1/WNK, CCT domain |
| Family | IPR050588 | With No Lysine (K) Ser/Thr Protein Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinase OSR1/WNK, CCT domain | With No Lysine (K) Ser/Thr Protein Kinase |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QDR7 | InterPro | 2247 | |||||
| UniProtKB:A0A8M9PVM9 | InterPro | 2154 | |||||
| UniProtKB:A0A8M9QM37 | InterPro | 2239 | |||||
| UniProtKB:A0A8M9QI77 | InterPro | 2234 | |||||
| UniProtKB:A0A8M9Q7T8 | InterPro | 2102 | |||||
| UniProtKB:A0AB32TXJ5 | InterPro | 2598 | |||||
| UniProtKB:A0AB32TXK2 | InterPro | 2599 | |||||
| UniProtKB:A0AB32TY75 | InterPro | 2506 | |||||
| UniProtKB:A0AB32TZN7 | InterPro | 2566 | |||||
| UniProtKB:A0AB32U0C3 | InterPro | 2454 | |||||
| UniProtKB:A0AB32U0Y1 | InterPro | 2591 | |||||
| UniProtKB:A0AB32U2A0 | InterPro | 2586 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers