Gene

wnk2

ID
ZDB-GENE-160114-3
Name
WNK lysine deficient protein kinase 2
Symbol
wnk2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have chloride channel inhibitor activity; potassium channel inhibitor activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including intracellular signal transduction; protein phosphorylation; and regulation of metal ion transport. Predicted to localize to cytosol. Orthologous to human WNK2 (WNK lysine deficient protein kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnk2 Human Ortholog
No data available
Associated With wnk2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Domain IPR024678 Serine/threonine-protein kinase OSR1/WNK, CCT domain
Family IPR050588 With No Lysine (K) Ser/Thr Protein Kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinase OSR1/WNK, CCT domain With No Lysine (K) Ser/Thr Protein Kinase
UniProtKB:A0A8M9QDR7 2247
UniProtKB:A0A8M9PVM9 2154
UniProtKB:A0A8M9QM37 2239
UniProtKB:A0A8M9QI77 2234
UniProtKB:A0A8M9Q7T8 2102
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA wnk2-201 (1) Ensembl 1,926 nt
mRNA wnk2-202 (1) Ensembl 8,040 nt
ncRNA wnk2-002 (1) Ensembl 483 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations