Gene

ece2b

ID
ZDB-GENE-131120-140
Name
endothelin converting enzyme 2b
Symbol
ece2b Nomenclature History
Previous Names
  • ece2 (1)
  • karneol (1)
  • si:ch211-117a13.2
  • si:dkey-83h2.6
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase activity. Involved in melanocyte differentiation and pigment cell development. Predicted to localize to integral component of membrane. Is expressed in liver. Orthologous to human ECE2 (endothelin converting enzyme 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Wang et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ece2b Human Ortholog
No data available
Associated With ece2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR008753 Peptidase M13, N-terminal domain
Domain IPR018497 Peptidase M13, C-terminal domain
Family IPR000718 Peptidase M13
Homologous_superfamily IPR024079 Metallopeptidase, catalytic domain superfamily
Homologous_superfamily IPR042089 Peptidase M13, domain 2
Domain Details Per Protein
Protein Length Metallopeptidase, catalytic domain superfamily Peptidase M13 Peptidase M13, C-terminal domain Peptidase M13, domain 2 Peptidase M13, N-terminal domain
UniProtKB:A0A8M6YSE0 783
UniProtKB:A0A8M6YUW2 794
UniProtKB:A0A024B5K5 765
UniProtKB:A0A8M6Z1E9 784
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ece2b-201 (1) Ensembl 2,573 nt
mRNA ece2b-202 (1) Ensembl 840 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations