Gene
foxo4
- ID
- ZDB-GENE-150311-1
- Name
- forkhead box O4
- Symbol
- foxo4 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within intracellular oxygen homeostasis and response to hypoxia. Predicted to be located in nucleus. Is expressed in blastoderm; brain; eye; muscle; and pericardial region. Orthologous to human FOXO4 (forkhead box O4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Shi et al., 2023
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR030456 | Fork head domain conserved site 2 |
| Domain | IPR001766 | Fork head domain |
| Domain | IPR032067 | FOXO protein, transactivation domain |
| Domain | IPR047409 | Forkhead box protein O4, forkhead domain |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Forkhead box protein O4, forkhead domain | Fork head domain | Fork head domain conserved site 2 | FOXO protein, transactivation domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1R3E6 | InterPro | 626 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance