Gene
pkd1l2b
- ID
- ZDB-GENE-141222-87
- Name
- polycystic kidney disease 1 like 2b
- Symbol
- pkd1l2b Nomenclature History
- Previous Names
-
- pkd1l2
- si:ch1073-128e6.1
- si:ch211-168k15.4
- si:ch211-168k15.5
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable calcium channel activity. Predicted to be involved in detection of mechanical stimulus. Predicted to be active in membrane. Is expressed in amacrine cell; ceratobranchial cartilage; pharyngeal arch cartilage; pharynx; and retinal ganglion cell layer. Orthologous to human PKD1L2 (polycystin 1 like 2 (gene/pseudogene)) and PKD1L3 (polycystin 1 like 3, transient receptor potential channel interacting).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from England et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa8579 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa21132 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41072 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa41073 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily | D-galactoside/L-rhamnose binding SUEL lectin domain | D-galactoside/L-rhamnose binding SUEL lectin domain superfamily | GAIN domain superfamily | GPS motif | PLAT/LH2 domain | PLAT/LH2 domain superfamily | Polycystic kidney disease type 2 protein | Polycystin | Polycystin-1 like, PLAT/LH2 domain | Polycystin cation channel, PKD1/PKD2 | Polycystin domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7F436 | InterPro | 124 | ||||||||||||||
| UniProtKB:E7F2U9 | InterPro | 702 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pkd1l2b-201
(1)
|
Ensembl | 2,597 nt | ||
| mRNA |
pkd1l2b-203
(1)
|
Ensembl | 3,187 nt | ||
| ncRNA |
pkd1l2b-002
(1)
|
Ensembl | 892 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-168K15 | ZFIN Curated Data | |
| Contained in | Fosmid | CH1073-128E6 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_021478036 (1) | 7313 nt | ||
| Genomic | GenBank:AL935125 (1) | 160047 nt | ||
| Polypeptide | UniProtKB:E7F2U9 (2) | 702 aa |