Gene
htra2-6
- ID
- ZDB-GENE-141219-11
- Name
- HtrA serine peptidase 2-6
- Symbol
- htra2-6 Nomenclature History
- Previous Names
-
- si:dkey-112g5.16
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable serine-type endopeptidase activity. Predicted to be involved in positive regulation of apoptotic process; programmed cell death; and proteolysis. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 8; Parkinson's disease; and motor neuron disease. Orthologous to human HTRA2 (HtrA serine peptidase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PDZ domain | PDZ domain 6 | PDZ superfamily | Peptidase S1C | Peptidase S1, PA clan |
|---|---|---|---|---|---|---|
|
UniProtKB:F1QYL0
|
194 | |||||
|
UniProtKB:A7YYA4
|
195 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
htra2 (1 of many)-205
(1)
|
Ensembl | 1,445 nt | ||
| mRNA |
htra2-201
(1)
|
Ensembl | 1,444 nt | ||
| mRNA |
htra2-205
(1)
|
Ensembl | 1,212 nt | ||
| mRNA |
si:dkey-112g5.16-001
(1)
|
Ensembl | 1,165 nt | ||
| mRNA |
si:dkey-112g5.16-002
(1)
|
Ensembl | 1,210 nt | ||
| mRNA |
si:dkey-112g5.16-004
(1)
|
Ensembl | 1,445 nt |
Interactions and Pathways
No data available
Plasmids
No data available