Gene

epob

ID
ZDB-GENE-141216-428
Name
erythropoietin b
Symbol
epob Nomenclature History
Previous Names
  • si:dkey-259i8.1 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have erythropoietin receptor binding activity and hormone activity. Predicted to be involved in nucleate erythrocyte development. Predicted to localize to extracellular region and integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic angiopathy; familial erythrocytosis 5; ischemia (multiple); and neurodegenerative disease (multiple). Orthologous to human EPO (erythropoietin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from She et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from She et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With epob Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial erythrocytosis 5 Alliance Erythrocytosis, familial, 5 617907
?Diamond-Blackfan anemia-like 617911
{Microvascular complications of diabetes 2} 612623
Associated With epob Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001323 Erythropoietin/thrombopoietin
Family IPR003013 Erythropoietin
Homologous_superfamily IPR009079 Four-helical cytokine-like, core
Domain Details Per Protein
Protein Length Erythropoietin Erythropoietin/thrombopoietin Four-helical cytokine-like, core
UniProtKB:A0A2R8QNK5 207
UniProtKB:A0A0R4IUI4 217
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations