Gene
nat8
- ID
- ZDB-GENE-141216-110
- Name
- N-acetyltransferase 8
- Symbol
- nat8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable N-acetyltransferase activity. Acts upstream of or within axis elongation and chordate embryonic development. Predicted to be located in membrane. Orthologous to several human genes including NAT8 (N-acetyltransferase 8 (putative)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Karmodiya et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-nat8 | N/A | Karmodiya et al., 2014 |
| MO2-nat8 | N/A | Karmodiya et al., 2014 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Acyl-CoA N-acyltransferase | GNAT domain | N-acetyltransferase, camello-type |
|---|---|---|---|---|---|
| UniProtKB:A0A8M1PSN6 | InterPro | 221 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-195e19.1-201
(1)
|
Ensembl | 4,172 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-195E19 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001342578 (1) | 4149 nt | ||
| Genomic | GenBank:CR559945 (1) | 186151 nt | ||
| Polypeptide | UniProtKB:A0A8M1PSN6 (1) | 221 aa |
- Nam, M.K., Moon, J.M., Kim, G.Y., Min Kim, S., Rhim, H. (2022) The Novel Human HtrA2 Ortholog in Zebrafish: New Molecular Insight and Challenges into the Imbalance of Homeostasis. Gene. 819:146263
- Fellous, A., Earley, R.L., Silvestre, F. (2019) Identification and expression of mangrove rivulus (Kryptolebias marmoratus) histone deacetylase (Hdac) and lysine acetyltransferase (Kat) genes. Gene. 691:56-69
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Karmodiya, K., Anamika, K., Muley, V., Pradhan, S.J., Bhide, Y., Galande, S. (2014) Camello, a novel family of Histone Acetyltransferases that acetylate histone H4 and is essential for zebrafish development. Scientific Reports. 4:6076
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