Gene

pigg

ID

ZDB-GENE-141215-6

Name

phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)

Symbol

pigg Nomenclature History

Previous Names

si:ch73-49o8.1

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human PIGG (phosphatidylinositol glycan anchor biosynthesis class G).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pigg Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with or without hypotonia, seizures, and cerebellar atrophy	616917
		[Blood group, EMM system]	619812

Associated With pigg Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR037674	GPI ethanolamine phosphate transferase 2, N-terminal
Domain	IPR045687	GPI ethanolamine phosphate transferase 2, C-terminal
Family	IPR002591	Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
Family	IPR039527	GPI ethanolamine phosphate transferase 2
Homologous_superfamily	IPR017850	Alkaline-phosphatase-like, core domain superfamily

Domain Details Per Protein

Protein	Length	Alkaline-phosphatase-like, core domain superfamily	GPI ethanolamine phosphate transferase 2	GPI ethanolamine phosphate transferase 2, C-terminal	GPI ethanolamine phosphate transferase 2, N-terminal	Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
UniProtKB:E7FE54 InterPro	972
UniProtKB:A0A8M3B8D1 InterPro	971

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	si:ch73-49o8.1-201 (1) Ensembl	Ensembl		4,242 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations