Gene

sh3rf2

ID

ZDB-GENE-141212-301

Name

SH3 domain containing ring finger 2

Symbol

sh3rf2 Nomenclature History

Previous Names

si:dkey-42a21.3
si:dkey-42a21.4 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in positive regulation of JNK cascade; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein ubiquitination. Orthologous to human SH3RF2 (SH3 domain containing ring finger 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sh3rf2 Human Ortholog

No data available

Associated With sh3rf2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR001452	SH3 domain
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR027370	Zinc finger, RING-type, eukaryotic
Family	IPR050384	Endophilin/SH3RF
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	Endophilin/SH3RF	SH3 domain	SH3-like domain superfamily	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type	Zinc finger, RING-type, conserved site	Zinc finger, RING-type, eukaryotic
UniProtKB:A0A8M3AHV6 InterPro	593
UniProtKB:A0A8M9QGN1 InterPro	769

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sh3rf2-201 (1) Ensembl	Ensembl	2,815 nt	Select Tool ZFIN BLAST
mRNA	sh3rf2-203 (1) Ensembl	Ensembl	6,264 nt	Select Tool ZFIN BLAST
ncRNA	sh3rf2-002 (1) Ensembl	Ensembl	882 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations