ZFIN is now using GRCz12tu for Genomic Data
Gene
csf3b
- ID
- ZDB-GENE-141212-221
- Name
- colony stimulating factor 3 (granulocyte) b
- Symbol
- csf3b Nomenclature History
- Previous Names
-
- Gcsf (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cytokine activity; granulocyte colony-stimulating factor receptor binding activity; and growth factor activity. Acts upstream of or within hemopoiesis and neutrophil chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including digestive system; heart; immune system; myeloid cell; and testis. Human ortholog(s) of this gene implicated in several diseases, including allergic cutaneous vasculitis; artery disease (multiple); cerebrovascular disease (multiple); leukemia (multiple); and lung disease (multiple). Orthologous to human CSF3 (colony stimulating factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Galdames et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Four-helical cytokine-like, core | GCSF/MGF |
|---|---|---|---|---|
| UniProtKB:A0A8M2BL23 | InterPro | 271 | ||
| UniProtKB:B5L332 | InterPro | 185 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers