ZFIN is now using GRCz12tu for Genomic Data
Gene
kcnt1b
- ID
- ZDB-GENE-141210-6
- Name
- potassium sodium-activated channel subfamily T member 1b
- Symbol
- kcnt1b Nomenclature History
- Previous Names
-
- si:dkey-21e5.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in potassium ion transport. Predicted to be located in plasma membrane. Is expressed in Kupffer's vesicle; brain; neural tube; otic vesicle; and peripheral olfactory organ. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 5 and developmental and epileptic encephalopathy 14. Orthologous to human KCNT1 (potassium sodium-activated channel subfamily T member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Silic et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nocturnal frontal lobe epilepsy 5 | Alliance | Epilepsy nocturnal frontal lobe, 5 | 615005 |
| developmental and epileptic encephalopathy 14 | Alliance | Developmental and epileptic encephalopathy 14 | 614959 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003148 | Regulator of K+ conductance, N-terminal lobe |
| Domain | IPR003929 | Calcium-activated potassium channel BK, alpha subunit |
| Domain | IPR013099 | Potassium channel domain |
| Family | IPR047871 | Calcium-activated potassium channel slowpoke-like |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnt1-202
(1)
|
Ensembl | 3,321 nt | ||
| mRNA |
kcnt1-204
(1)
|
Ensembl | 3,363 nt | ||
| mRNA |
kcnt1b-201
(1)
|
Ensembl | 3,385 nt | ||
| mRNA |
kcnt1b-203
(1)
|
Ensembl | 2,037 nt |
Interactions and Pathways
No data available
Plasmids
- Genome Browsers
- Comparative Orthology
- Alliance