Gene

taok1b

ID

ZDB-GENE-141024-1

Name

TAO kinase 1b

Symbol

taok1b Nomenclature History

Previous Names

zgc:112307

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in positive regulation of JNK cascade; positive regulation of stress-activated MAPK cascade; and regulation of cytoskeleton organization. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm. Orthologous to human TAOK1 (TAO kinase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:112307 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With taok1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Developmental delay with or without intellectual impairment or behavioral abnormalities	619575

Associated With taok1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Family	IPR051234	TAO Serine/Threonine-Protein Kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site	TAO Serine/Threonine-Protein Kinase
UniProtKB:A0A0R4IP53	InterPro	1001

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	taok1b-201 (1) Ensembl	Ensembl	5,341 nt	Select Tool ZFIN BLAST
mRNA	taok1b-202 (1) Ensembl	Ensembl	1,053 nt	Select Tool ZFIN BLAST
mRNA	taok1b-203 (1) Ensembl	Ensembl	3,122 nt	Select Tool ZFIN BLAST
mRNA	taok1b-204 (1) Ensembl	Ensembl	3,257 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations