Gene

slc4a3

ID
ZDB-GENE-141006-1
Name
solute carrier family 4 member 3
Symbol
slc4a3 Nomenclature History
Previous Names
  • Ae3 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable anion:anion antiporter activity and inorganic anion exchanger activity. Acts upstream of or within cardiac muscle cell action potential. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in fin and fin bud. Used to study short QT syndrome. Orthologous to human SLC4A3 (solute carrier family 4 member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Shmukler et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Thorsen et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc4a3 Human Ortholog
No data available
Associated With slc4a3 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018241 Anion exchange, conserved site
Domain IPR011531 Bicarbonate transporter, C-terminal
Domain IPR013769 Band 3 cytoplasmic domain
Family IPR001717 Anion exchange protein
Family IPR002979 Anion exchange protein 3
Family IPR003020 Bicarbonate transporter, eukaryotic
Homologous_superfamily IPR016152 Phosphotransferase/anion transporter
Domain Details Per Protein
Protein Length Anion exchange, conserved site Anion exchange protein Anion exchange protein 3 Band 3 cytoplasmic domain Bicarbonate transporter, C-terminal Bicarbonate transporter, eukaryotic Phosphotransferase/anion transporter
UniProtKB:A0A0G2KM71 739
UniProtKB:A0A096X8J9 157
UniProtKB:A0A096X8J7 1170
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations